The modern cohort selection and analysis interface


Glowing Bear is a modern data selection interface, enabling cohort selection and exploratory analyses. It is built on i2b2/tranSMART data model with strong community support. Glowing Bear provides:

  • Support for queries on longitudinal and sample data  
  • Cross-study, ontology-based variable harmonisation  
  • Decoupled user interface, built on Angular  
  • API-level enforced security 
  • Standardized installation with Docker


Background information 

In 2016-2017 the i2b2 tranSMART Foundation initiated the 17.1 project. The Hyve has been actively involved in the development of this new and updated version of tranSMART. Added functionalities include support for longitudinal data sets and the option to save and re-execute queries. 

The 17.1 project, however, did not include an adaptation of the tranSMART user interface to support the new functionalities. Therefore, The Hyve started project ‘Glowing Bear’: the development of a new, modern user interface for tranSMART 17.1 that would unlock the full potential of its added functionalities. 

Glowing Bear was officially launched in September 2018. In May 2019, Glowing Bear 2.0 was released with two improvements: New sample query and subscription; and Improved user interface workflow (more on this).



  • Tree-structured data overview with variable search
  • Patient cohort selection with complex nested queries
  • Dataset selection on variables of interest and data export
  • Patient query subscription: receive email notifications when your cohort is updated
  • Data table and improved export, with flexible dimension organisation
  • Cross table for data exploration
  • Keycloak for convenient authentication and authorization management
  • Glowing Bear v.2.0 release with biosample query and subscription feature
  • Dockerization of Glowing Bear and its components
  • Interactive visual analytics with the Fractalis platform (IN DEVELOPMENT)




How scalable is Glowing Bear? 

Glowing Bear is demonstrated to be scalable up to 300k patients and 500M observations, and even larger cohorts were planned. 

What browsers are supported? 

We support the Latest versions of Chrome, Firefox, Safari and Edge. IE is partially working, please choose one of the other browsers if you have a problem using IE.

Is Glowing Bear free?

Glowing Bear is an open source tool, meaning that the most recent version can be installed on your computer for free. However, implementation of new features, maintenance and data loading are paid services.

Who has adopted Glowing Bear? 

Academic hospitals, Universities and top clinic centers are currently using Glowing Bear, including Princess Máxima Center for Pediatric Oncology, the Netherlands Twin Registry (NTR), and Leiden University Medical Center (LUMC).


Go to Glowing Bear Demo or read more on Glowing Bear. You can also contact us for further inquiries here.